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Wednesday, January 29, 2020

Applying Thermal Expansion Essay Example for Free

Applying Thermal Expansion Essay Complete the following problems and exercises using complete sentences and showing all work where appropriate. 1. The temperature of the Suns interior is about 107 degrees. Does it matter whether this is degrees Celsius or kelvins? Defend your answer. No, it DOESNt matter whether this is in degrees Celsius or kelvins, since the DIFFERENCE between these scales is ONLY ~ 273 of either measure, and that is ABSOLUTELY NEGLIGIBLE w.r.t. the magnitude of the number 10^7. However, what is more important, perhaps, is that your value of 10^7 is itself a rather loose characterization. Modern  solar evolutionary models suggest rather that the Suns T_c is ~ 1.5 x 10^7 (degrees Celsius or kelvins) instead of merely ~ 10^7. (Our understanding of solar physics is certainly such that an error of a factor of ~ 1.5 in its central temperature would be considered way out of all reasonable possibility!) Of course the numerical factor in front of 10^7 would matter even more if one were using the (non-scientific) Fahrenheit scale. Once again, however (unlike National Geographic magazine, which should hang its head in shame over some of its conversions), one would NOT say that the Suns central temperature was about 2.7 x 10^7 and 32 degrees Fahrenheit! 2. What happens to the gas pressure within a sealed gallon can when it is heated? Cooled? Why? The gases in general obey the gas laws. As per the law the pressure,volume and temperature of the gas is related as: P1V/T1 =P2V2/T2; WhereP1 is pressure at stage 1, V1 is volume at stage 1 and T1 is temperature (Kelvin) for stage 1,and P2,V2 and T2 are the pressure,volume and temperature for stage 2. Now, if a gas contained in a sealed gallon is heatedor cooled the volume of the gas is constant but pressure and temperature will adjust u=in such a way that the : P1/T1 =P2/T2 If T2 is more than T1,then( heating the gas ) P2= P1*T2/T1 as T2 T1 so P2 will bve more than P1,hence, the pressure will increase. If T2

Tuesday, January 21, 2020

The Effect of Temperature on Air Pressure :: science

The Effect of Temperature on Air Pressure DESCRIPTION: My project consists of a series experiments to determine the effect of air pressure in a given environment at various temperatures. The experiments I chose to conduct are: 1) Heat an ordinary pop can on a hot plate and then putting the can upside down in cold water to see the effect of a fast change in temperature. 2) Partially full milk jug with hot water, put the cap on tightly, and let it sit for one hour to see the effect of a slow change in temperature. 3) Setting a small piece of paper on fire and then putting it inside a plastic bottle. Before the flame goes out, a pealed hard-boiled egg will be placed over the opening. PROBLEM: The problem is to determine the effects of air pressure at different temperatures. Since we cannot see air, we will attempt to determine if air exerts a force? HYPOTHESIS: My hypothesis for: 1) the experiment with the pop can is that the can will crush because of a drastic change in temperature. 2) the experiment with the milk jug and the hot water is that the milk jug will remain the same. 3) the experiment with the egg and the bottle is that the egg will not be sucked in the bottle. PROCEDURE: For the first experiment the procedure is: 1) Heat an ordinary pop can on a hot plate. 2) After about fifteen minutes take the can off the hot plate and put it upside-down in a pan of cold water. 3) Record my observations on a piece of paper. 4) Write my conclusions in my science fair logbook. For the second experiment my procedure is: 1) Get an empty gallon milk jug at room temperature. 2) Heat to water to just before the boiling point on a hot plate. 3) Fill the milk jug about quarter of the way with hot water. 4) Put the lid on tightly 5) Wait one hour and record my observations and conclusions. For the third experiment my procedure is: 1) Get a medium sized bottle. 2) Peel a hard boiled egg. 3) Light a small piece of paper on fire and put it inside the bottle. 4) Before the flame goes out put the pealed egg over the opening of the bottle. 5) Record my observations on a piece of paper.

Monday, January 13, 2020

Pfizer Marketing Strategies Essay

Pfizer Inc., discovers, develops, manufacturers, and markets leading prescription medicine for humans and animals and many of the world’s best-known consumer brands. Their innovative, value-added products improve the quality of life of people around the world and help them enjoy longer, healthier, and more productive lives. The company has three business segments: health care, animal health and consumer health care. The top three worldwide pharmaceutical companies in sales are from GlaxoSmithKline, Pfizer and Merck respectively. In 2001, Pfizer increased its’ market share and became the sales leader. They have continued to lead the industry since. The main reason for their tremendous growth is that their pharmaceutical products are able to improve the quality of life of their customers. Those products are Aricept, Celebux, Diflucan, Lipitor, Neurontin, Norvasc, Viagra, Zithromax, Zoloft and Zyrtec. Research and development is vital to the success of any pharmaceutical company. Pfizer spent 7.1 billion on research and development in 2003; this is the only pharmaceutical company that is capable of investing this much. Their future, as one company, with a single purpose and mission, is sharply defined. Pfizer Inc. wants to be the company that does more good, for more people, than any other on the planet. Innovation is critical to improving health and sustaining Pfizer’s growth and profitability. They are deeply committed to meeting the needs of their customers, and we constantly focus on customer satisfaction. Pfizer is now implementing a strategy to drive performance within the global business, building on the business model and management ethic that they applied in the United States. The most important priority is to improve sales performance through the launch of new pharmaceutical products, encourage doctors to continue to prescribe existing products, and attempt to increase consumption and enlarge the over-the-counter market. Pfizer is a strong and reliable brand, with a solid competitive position and diversified product line that appeals to a wide customer base. However, Pfizer needs to communicate with their clients more effectively in order to capitalize on their opportunities. Their current objective focuses heavily on increasing profitability and sales volume of the new products, such as Lipitor,  Norvasc, Celebrex and Neurontin. They are seeking to increase efficiency by reorganizing of the structure of the company. Pfizers’ focus on research and development is matched by an equally strong emphasis on marketing. The company promotes its human pharmaceutical products to health care providers including doctors, nurse practitioners, physician assistants, pharmacists, pharmacy benefits managers, and managed care organizations. Pfizer also promotes its products directly to consumers in the U.S. via direct-to-consumer (DTC) print and television advertising. Pfizer has responded to the Food and Drug Administration’s 1997 decision to loosen restrictions on DTC advertising of prescription drugs by increasing DTC promotional spending each year Pfizer’s strong marketing and sales operations have enabled the company to become the â€Å"partner of choice† for the marketing of innovative products developed by others. Pfizer is extremely skilled in creating alliances with other pharmaceutical companies via co-promotion agreements. Through co-promotion and licensing agreements, Pfizer promotes and markets such highly promising products as Celebrex, Bextra, Aricept, and so on with alliance partners. Pfizer provides cash, staff, and other resources to further develop, market, promote, and sell the products in exchange for a share of revenues. For the over-the-counter market, Pfizer advertises in newspapers, magazines and uses outside media, especially for essential pharmaceutical products. An example would be the cardiovascular medicine â€Å"LIPITOR†. Potential customers gain product knowledge through advertisements when reading newspapers and popular magazines. For doctors, Pfizer spends a substantial amount of money for physician-type advertisements, such as small catalogs, relevant posters, printed 3D diagram regarding the specified product because the doctor is their main customer. Once the patient is exposed to the advertisements inside the clinic, they have more product knowledge and confidence. Pfizer continues to have sales promotions each year to support the 2-3 products they develop annually. These sales promotions are focused on  hospitals and general practitioners. Before the new product is going to launch, Pfizer announces relevant details to these people first and advises them of all of the available support. Once launched, a clinical study paper and samples are delivered to the doctors when Pfizer representatives are visiting them. Antibiotics are classified into four groups: Penicillin, Quinolones, Macrolides and Cephalosporins. Patients will develop a resistance through continued use of same antibiotic, which is why Pfizer continually develops new antibiotics. Sales promotion, advertising, and product knowledge are all very important aspects of marketing for Pfizer to launch their new products. While Pfizer has a number of strong products in its portfolio, it is Viagra that has received a large amount of attention recently and its success will be important for Pfizer. However, the huge cost of Viagra has been a highly discussed issue, with a number of governments struggling to reach decisions over reimbursement issues. However, Viagra’s high cost may lead to the use of cheaper, alternative treatment for the condition. There have also been a number of safety issues surrounding the use of Viagra. Because of the high consumer awareness of Viagra due to extensive media coverage, the continued safety concerns, combined with the impending launch of alternative oral treatments, this could have a significant adverse affect on the sales of Viagra. Pfizer appears to have continued high expectations for Viagra, possibly implying an over dependence on the success of one product. The high sales and marketing investment by Pfizer to promote Viagra could damage the company’s profitability if revenues from Viagra do not live up to expectations. Pfizer is a company that has a stronghold on its’ market, due to having superior research and development department, as well as one of the most innovative ways to approaching potential customers and business partners. All of this contributes to their competitive advantage and enables the company to always stay a step ahead of their competitors. Although the health care industry is ever changing and threats and opportunities often appear, Pfizer has a stable base for the future in this business field. As the company motto states: â€Å"Life is our Life’s Work!†

Sunday, January 5, 2020

King George III Biography

George III was King of Great Britain and King of Ireland during the American Revolution. Much of his reign, which lasted from 1760 to 1820, was colored by his ongoing problems with mental illness. During the last decade of his life, he was incapacitated to the degree that his eldest son ruled as Prince Regent, giving name to the Regency Era. Fast Facts: King George III Full Name:  George William FrederickKnown For:  King of Great Britain and Ireland during the American Revolution, suffered from acute and debilitating bouts of mental illnessBorn:  June 4, 1738 in London, EnglandDied:  January 29, 1820 in London, EnglandSpouses Name: Sophia Charlotte of Mecklenburg-StrelitzChildren: 15 Early Years Born June 4, 1738, George William Frederick was the grandson of Great Britain’s King George II. His father, Frederick, the Prince of Wales, though estranged from the king, was still the heir apparent to the throne. George’s mother, Princess Augusta of Saxe-Goethe, was the daughter of a Hanoverian duke. Although sickly as a child—George was born two months prematurely—he soon grew stronger, and he and his younger brother Prince Edward moved with their parents to the family home in London’s exclusive Leicester Square. The boys were educated by private tutors, as was common for the children of royalty. Young George was precocious, and he could read and write several languages fluently, as well as discuss politics, science, and history, by the time he was an adolescent. Heritage Images / Getty Images In 1751, when George was thirteen, his father, the Prince of Wales, died unexpectedly, following a pulmonary embolism. Suddenly, George became the Duke of Edinburgh and the heir apparent to the British crown; within three weeks, his grandfather made him Prince of Wales. In 1760, George II passed away at the age of seventy, leaving 22-year-old George III to take the throne. Once he became king, he soon realized it was vital for him to find a suitable wife to bear his sons; the very future of the empire depended on it. Seventeen-year-old Sophia Charlotte of Mecklenburg-Strelitz was the daughter of a duke, privately educated, and had no scandals attached to her name, making her the perfect bride for a king. George and Charlotte did not even meet until their wedding day in 1761. By all reports, the two of them had a mutually respectful marriage; there was no infidelity on either of their parts, and they had fifteen children together. Charlotte and George were avid patrons of the arts, and were especially interested in German music and composers like Handel, Bach, and Mozart. During the first few years of Georges reign, the British Empire was financially shaky, due in part to the aftershocks of the Seven Years War (1756 to 1763). The British colonies were generating little revenue, so strict tax laws and regulations were enacted to bring extra money to the crown coffers. DEA / G. NIMATALLAH / Getty Images Revolution in the Colonies After decades of no representation in Parliament, and resentful of the extra tax burdens, the colonies in North America rebelled. Americas founding fathers famously detailed the transgressions perpetrated against them by the King in the Declaration of Independence: The history of the present King of Great Britain is a history of repeated injuries and usurpations, all having in direct object the establishment of an absolute Tyranny over these States.   After a series of setbacks in North America, Georges advisor Lord North, then the Prime Minister, suggested the king take a break from trying to handle the dissent in the colonies. North proposed that Lord Chatham, William Pitt the Elder, step in and take power of oversight. George refused the idea, and North resigned following General Cornwallis defeat at Yorktown. Eventually, George accepted that his armies had been defeated by the colonists, and authorized peace negotiations. Bettmann Archive / Getty Images Mental Illness and the Regency Wealth and status could not protect the king from suffering extreme bouts of mental illness—some so severe that he was incapacitated and unable to make decisions for his realm. George’s mental health issues were well-documented by his equerry, Robert Fulke Greville, and Buckingham Palace. In fact, he was heavily monitored by staff at all times, even while he slept. In 2018, the records were made public for the first time. In 1788, Dr Francis Willis wrote: â€Å"H.M became so ungovernable that recourse was had to the strait waistcoat: His legs were tied, he was secured down across his Breast, in this melancholy situation he was, when I came to make my morning Enquiries.† Scientists and historians have debated for over two centuries about the cause of the famous â€Å"madness.† One 1960s study indicated a link to the hereditary blood disorder porphyria. People suffering from porphyria experience acute anxiety, confusion, and paranoia. However, a 2010 study published in the Journal of Psychiatry concluded that George probably didn’t have porphyria at all. Led by Peter Garrard, professor of neurology at St. George’s University of London, researchers did a linguistic study of George’s correspondences, and determined that he suffered from â€Å"acute mania.† Many of the characteristics of George’s letters during his periods of illness are also seen in the writings and speech of patients today who are in the midst of the manic phase of illnesses like bipolar disorder. Typical symptoms of a manic state are compatible with contemporary accounts of George’s behavior. It is believed that Georges first bout of mental illness surfaced around 1765. He spoke endlessly, often for hours, and sometimes without an audience, causing himself to foam at the mouth and lose his voice. He rarely slept. He shouted unintelligibly at advisors who spoke to him, and wrote lengthy letters to anyone and everyone, with some sentences being hundreds of words long. With the king unable to function effectively, his mother Augusta and  Prime Minister Lord Bute  somehow managed to keep Queen Charlotte unaware of what was happening. In addition, they conspired to keep her ignorant of the Regency Bill, which decreed that in the event of George’s full incapacity, Charlotte herself would then be appointed Regent. Some twenty years later, after the Revolution had ended, George had a relapse. Charlotte was, by now, aware of the existence of the Regency Bill; however, her son, the Prince of Wales, had designs of his own on the Regency. When George recovered in 1789, Charlotte held a ball in honor of the Kings return to health—and deliberately failed to invite her son. However, the two of them formally reconciled in 1791. Although he remained popular with his subjects, George eventually descended into permanent madness, and in 1804, Charlotte moved into separate quarters. George was declared insane in 1811, and agreed to be placed under Charlottes guardianship, which remained in place until Charlottes death in 1818. At the same time, he consented to his empire being placed in the hands of his son, the Prince of Wales, as Prince Regent. Grafissimo / Getty Images Death and Legacy For the last nine years of his life, George lived in seclusion at Windsor Castle. He eventually developed dementia, and didnt seem to understand that he was the king, or that his wife had died. On January 29, 1820, he died, and was buried a month later at Windsor. His son George IV, the Prince Regent, succeeded to the throne, where he reigned for ten years until his own death. In 1837, Georges granddaughter Victoria became Queen. Although the issues addressed in the Declaration of Independence paint George as a tyrant, twentieth-century scholars take a more sympathetic approach, viewing him as a victim of both the changing political landscape and his own mental illness. Sources â€Å"George III.†Ã‚  History.com, AE Television Networks, www.history.com/topics/british-history/george-iii.â€Å"What Was the Truth about the Madness of George III?†Ã‚  BBC News, BBC, 15 Apr. 2013, www.bbc.com/news/magazine-22122407.Yedroudj, Latifa. â€Å"Mad King George III Mental Health Records REVEALED in Buckingham Palace Archives.†Ã‚  Express.co.uk, Express.co.uk, 19 Nov. 2018, www.express.co.uk/news/royal/1047457/royal-news-king-george-III-buckingham-palace-hamilton-royal-family-news.